NMN (Nicotinamide Mononucleotide)
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At what age should one take NMN? After all, NMN levels decline during aging, but are still fairly high when people are young (like in their twenties). First, to our knowledge, there are no studies demonstrating potential adverse effects when taking NMN starting at a young age. NMN is a molecule ...
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Can NMN help to slow down aging?
RESEARCH UPDATE ABOUT NMN NMN (nicotinamide mononucleotide) is currently one of the most researched and popular substances to slow down aging. NMN is a substance that occurs naturally in our body. NMN is a precursor to NAD+. NAD+ is a very important molecule for every cell in our body. NAD+ i... -
Can NMN pass the cell membrane and can I take it orally?
Online, there can be found a lot of conflicting information about the absorbability and oral bioavailability of NMN. It was previously thought that NMN could not be absorbed by cells (NMN would be too large to go through the cell membrane). Many online articles still claim this. However, in 2019... -
Can you take NMN if you have a MTHFR mutation? Or suffer from reduced methylation?
NMN is a substance that has shown to reduce various aging symptoms in studies (R,R,R,R,R), and has shown to improve insulin resistance, muscle metabolism and aerobic metabolism in humans (R,R,R). However, when you take NMN, some waste products of NMN require proper methylation to be disposed. So... -
Can you take NMN orally? Or only sublingually?
What’s the best, most effective way to take NMN? Orally? Sublingually (melting it under the tongue)? Or is NMN only available through injection? Some people claim that NMN cannot be taken orally. Others claim you have to take it sublingually and that just swallowing a pill is not going to cut ... -
Does your NMN have a short shelf life, degrading into nicotinamide after a while?
Some people claim that NMN can degrade into nicotinamide (a form of vitamin B3). NMN could indeed be converted into nicotinamide or vitamin B3. However, this mostly concerns only a small fraction of the total NMN. We nonetheless recommend ideally storing NMN in a cool place (e.g. refrigerator) ... -
Do I need to take methyl donors with my NMN?
It depends. There is a theoretical assumption that one would need to take extra methyl donors given NMN uses up methyl groups in order to be degraded and excreted (methyl groups are small molecules that are attached to other molecules to process them). However, this has not really been born out ... -
Do you need to combine NMN with TMG (trimethylglycine)?
NOVOS looked into adding TMG (trimethylglycine) to our NMN. After all, NOVOS is a big proponent of proper methylation and epigenetic approaches to longevity and health. However, TMG can cause in some people digestive issues and sleep problems. We also think TMG is already too deep into the meth... -
Ideally, you store NMN in a cool, dry place. You can also store it in the refrigerator. Keep it out of light and avoid too high temperatures.
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How much NMN should I take? Dr. David Sinclair takes a very high dose of 1,000 mg per day
The minimum recommended dose of NMN is 2 capsules (2 × 125 mg of NMN) per day, 1 to 2 times daily. We advise to take between 250 mg and 500 per day on a regular basis. Regarding NMN dosing, some people refer to Harvard Professor David Sinclair who takes a very high dose of 1,000 mg per day, and ... -
Is liposomal NMN better than normal NMN?
It's not necessary to take liposomal NMN. Why? All studies done in animals that demonstrate beneficial effects of NMN used non-liposomal NMN; scientists added normal NMN to the drinking water or food. Also, all studies hitherto done in humans use non-liposomal NMN. These studies showed various ... -
NMN is very likely better than NR. NMN is one step further in the pathways that converts NAD boosters (like NMN and NR) into NAD. Also, NMN is more stable in the blood. Scientific research seems to indicate the NMN is better than NR. For example, NMN seems to have more beneficial effects on va...
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Is NMN well absorbed as oral capsules? Is there anything I should know about NMN in capsule form?
NMN research uses regular, powdered NMN – not sublingual, not liposomal. From these studies, we can arrive at dosages that demonstrate favorable health outcomes, regardless of what percentage of that oral dosage is absorbed. That is ultimately what’s important to know. And that dosage, where bene... -
Is the NMN in NOVOS Boost soy-free, gluten-free, non-GMO and vegan?
Yes, our NMN is soy-free, gluten-free, non-GMO and vegan. Our NMN supplements are also high-quality, high-purity and contain more stable, next-generation NMN. -
Is your NMN high-quality? Is it third-party tested? Is it safe?
NOVOS' NMN (nicotinamide mononucleotide) comes from one of the largest, most reputable and science-based manufacturers of NMN in the world. It has been tested by a 3rd party via HPLC, LC-MS, LC-MSMS, 1HNMR, 13CNMR, etc. It is >99% pure and free of heavy metals, bacteria, yeast, mold, etc. You ... -
Our NMN Boost is manufactured in the United States in an GMP-certified, FDA-approved facility. For competitive reasons, we don't divulge our US-based manufacturing partners. Our NMN is third-party tested by an independent lab demonstrating high purity (>99 percent) of our NMN, and has been te...
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NMN has been brought into the public limelight by scientists such as professor David Sinclair of Harvard University and Professor Shin-Ichiro Imai of Washington University, who showed in studies that NMN could substantially ameliorate various symptoms of aging. NMN is a molecule that occurs natu...
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What's the best NMN supplement available?
NMN supplements have flooded the market. The rising popularity of NMN as a supplement to slow down aging stems from many scientific studies showing that NMN can slow down aging, and by positive claims about NMN as a longevity ingredient by well-known researchers, like Professor David Sinclair fr... -
You can take NMN twice a day or once a day (preferably in the morning, given it can sometimes give a boost of energy).
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Which ingredients does NMN work with synergistically?
NMN works synergistically with NMN works synergistically with pterostilbene, fisetin, alpha-ketoglutarate, glycine, lithium, vitamin C and glucosamine. These are many of the ingredients in our NOVOS Core supplement. In fact, we specifically developed our Core supplement to have synergistic effe... -
Why does David Sinclair take NMN and not NR?
Dr. David Sinclair has publicly shared his NMN dosing routine, so naturally we receive a lot of questions about his dosing. Note that Dr. David Sinclair is not affiliated with NOVOS, and the following is our independent scientific analysis of NMN research and ideal dosages. Dr. David Sinclair, p... -
NMN is a very difficult molecule to manufacture. Until very recently, it was almost prohibitively expensive to manufacture. New production processes enabled the price to go down significantly, but NMN is still a very expensive supplement to produce, especially if you want to achieve high-quality...
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Why is your NMN more stable or better?
Not all NMN is the same, despite being the "same molecule". Stability of NMN is largely determined by the surrounding water molecules and the organization of the NMN with other surrounding NMN molecules. The water molecules are polar (having different electric charges on different sides), which c... -
Why NOVOS' NMN is superior to many other NMN supplements
How is NOVOS' NMN different compared to many other brands? NOVOS' NMN is unique given our NMN: - Has been double-checked by two independent third-party labs - Is supported by a scientific advisory board of top longevity experts - Our NMN is very high purity (more than 99 percent NMN) - With ...