Ingredients & Other Supplements
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Are supplements necessary? Do I need to take supplements?
Do I need to take supplements? And for the rest of my life? There are a lot of misconceptions about supplements. Not in the least from governments, various MDs and health experts. Let’s start by saying that supplements are a complex matter. Ignorance and oversimplification are one important rea... -
Can I combine NOVOS with a multivitamin or other vitamins and minerals?
You can take multivitamins with NOVOS Core and/or NOVOS Boost. In fact, we developed NOVOS products specifically to be combined with multivitamins without issue. Regarding the best vitamins, minerals and other micronutrients to take with NOVOS products, we wrote an article about this topic here... -
Could glucosamine cause insulin resistance or higher sugar (glucose) levels?
When creating NOVOS Core, we took great care to research the topic of glucosamine and insulin resistance. More recent studies show that glucosamine does not increase insulin resistance. Also, glucosamine has various other benefits that are more important, like improving mitochondrial biogenesis... -
Could long-term lithium intake cause kidney damage?
Microdosed lithium has been shown to slow down aging and exert various protective effects on cells, especially brain cells. That’s why microdosed lithium is often used as an anti-aging supplement (R,R,R,R,R), or as a way to reduce the risk of Alzheimer’s disease and other neurodegenerative disea... -
David Sinclair supplements: What anti-Aging supplements does Harvard scientist David Sinclair take?
Note that Dr. David Sinclair is not affiliated with NOVOS. NOVOS is an independent Public Benefit Corporation with a diverse team of world renowned longevity scientists; this post is an independent analysis of Dr. David Sinclair’s supplementation routine. David Sinclair, 54 years old, is a profe... -
Do antioxidants slow down aging? Does NOVOS contain antioxidants?
Many people still believe that antioxidants slow down aging. Antioxidants are substances like vitamin A, vitamin E, coenzyme Q10, beta-carotene, acetyl-cysteine, and so on. Antioxidants neutralize free radicals. Free radicals are mainly a by-product of our metabolism. Free radicals are highly r... -
Does Eating or Drinking Collagen Supplements Improve Skin Wrinkles?
Taking ingredients by mouth to improve skin health is becoming ever more popular. And of the most well-known oral skin-care ingredients is collagen. When taken by mouth, it’s claimed that collagen can improve wrinkles, fine lines, skin elasticity, and general skin health. But does it work? Wha... -
Human biology is a complex system. While DHT is one factor relevant to hair loss, there are others as well. It’s also important to consider the degree to which glycine impacts DHT and the likelihood that this process will impact your hair loss. Glycine has a number of benefits that can favorably...
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Do I need to take calcium? How much calcium? Why not take calcium via milk or dairy?
Regarding calcium intake, it's important to make sure you consume enough calcium every day. Even when consuming dairy, many people don't reach the required levels of calcium. Also, dairy, especially milk, can accelerate aging (see further down). Therefore, we are proponents of taking calcium su... -
First, we know that NOVOS ingredients get properly absorbed, given many studies demonstrate that when the ingredients are taken orally, they lead to beneficial effects in different organisms and humans. This means that the ingredients are absorbed, are sufficiently stable, and can reach the req...
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How much calcium is there in NOVOS?
NOVOS contains 1100 mg of alpha-ketoglutarate + 200 mg of calcium (a total of 1300 mg of calcium alpha-ketoglutarate). An adult needs around 1000 mg of calcium per day. This can be somewhat more per day (e.g. 1250 mg per day). However, make sure not to take calcium supplements that contain larg... -
Is NMN better than NR? NMN vs NR (Nicotinamide mononucleotide versus nicotinamide riboside)
NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) supplements are both often touted as two of the most promising supplements to slow down aging. NR and NMN are precursors to NAD+ (nicotinamide adenine dinucleotide). This means NR and NMN are converted into NAD+. NAD+ is a very im... -
Metformin versus pterostilbene, fisetin, glucosamine and berberine
Metformin Versus Other Anti-Aging Supplements | Which Is Best For Longevity? Metformin is one of the most popular, off-label, anti-aging prescription drugs. There are other drugs that show promise to extend lifespan, like rapamycin or selegiline, but metformin is arguably the most well-known, a... -
Pterostilbene versus resveratrol
Pterostilbene is a natural molecule found in fruits, vegetables and nuts. Blueberries are often quoted as one of the richest sources of pterostilbene. However, the amount of pterostilbene in blueberries is much lower than you can find in food supplements or lower than the amounts used in scientif... -
The 13 best anti-aging supplements, science-based
There are countless supplements claiming that they are “anti-aging”. Unfortunately, almost none of them are. Most anti-aging supplements contain ingredients that: Are based on outdated ideas (e.g., that antioxidants slow down aging – they don’t). Are based on little to no science. Contain too ... -
Top anti-aging supplements for healthy joints and osteoarthritis
Osteoarthritis is the wearing down of joints, especially of the cartilage that lines the joints. It’s also called degenerative joint disease or “wear-and-tear” arthritis. Osteoarthritis is very common. Our joints are the Achilles heel of the musculoskeletal system; they are prone to wearing dow... -
What is the role of hyaluronic acid (HA) in cancer prevention and cancer growth?
What is the role of hyaluronic acid (HA) in cancer prevention and cancer growth? Some studies in cancer research show that specific cancers, such as pancreatic cancer, use hyaluronic acid as food. Pancreatic cancer cells feed on hyaluronic acid to fuel their growth and survival (R). However, thi... -
Natural origin of lithium Lithium is a mineral present in igneous rocks. From these rocks, lithium seeps into water springs and rivers, and into drinking water and foods, such as potatoes, tomatoes, cabbage, nuts, fish and cereals. People consume lithium on a daily basis via mineral water and ...
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Which form of calcium should I take?
The precise form of calcium doesn't matter that much. There are a lot of internet articles touting one form above the other, but for calcium most forms are ok. Calcium carbonate is widely used and is an adequate form of calcium supplementation. This is however not the case for some other substan... -
Which vitamin and mineral supplements should I take?
Most of the minerals, vitamins and other supplements contain too low doses, the wrong forms (e.g. magnesium oxide instead of magnesium malate), or wrong combinations (e.g. calcium with iron, or copper with zinc, which inhibit each other's absorption). We explain more about the best supplements t... -
Why does NOVOS not contain alpha-lipoic acid (ALA)?
When formulating NOVOS Core, we looked closely into alpha-lipoic acid (ALA). Alpha lipoic acid is often promoted as an anti-aging substance. There are studies demonstrating beneficial effects of alpha-lipoic acid (ALA), mainly in rodents but also in humans. For example, ALA could perhaps reduce ... -
There are quite a few misunderstandings about glucosamine. And there are also things that most people don’t know about glucosamine, like that it has effects far beyond improving joint health, like extending lifespan or reducing inflammation. Most people know glucosamine as a supplement to impro...
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Why does NOVOS use glycine instead of trimethylglycine (TMG) or betaine?
Trimethylglycine (TMG), also called betaine, is a substance that is sometimes recommended for health or longevity purposes, mainly to improve methylation (which is the process of adding small molecules called methyl groups to the DNA to regulate gene expression). TMG was one of the many substanc... -
Why do you use fisetin? Is fisetin better than quercetin?
Fisetin is a naturally occurring substance found in fruits and vegetables, such as strawberries, apples, grapes, onions, and cucumbers. Fisetin is a flavonoid. Flavonoids are substances that give fruits and vegetables their bright colors (like yellow, orange and blue) and play a major role in co...